Enantioselective Total Synthesis of (−)-Lansai B and (+)-Nocardioazines A and B
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چکیده
منابع مشابه
Enantioselective total synthesis of (-)-lansai B and (+)-nocardioazines A and B.
The concise total syntheses of the bis(pyrroloindolines) (-)-lansai B and (+)-nocardioazines A and B are reported. The key pyrroloindoline building blocks are rapidly prepared by enantioselective formal [3+2] cycloaddition reactions. The macrocycle of (+)-nocardioazine A is constructed by an unusual intramolecular diketopiperazine formation.
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2014
ISSN: 1433-7851
DOI: 10.1002/anie.201402571